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在儿科腹膜腹中保守抗生素治疗的结果:一项回顾性观察性研究
Francesca Hoegger1, Sandra Andrea Asner2, Sophie Fries3
1Service of Pediatrics, Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
European journal of pediatrics
|September 17, 2025
概括
用抗生素进行保守的治疗对于儿科外腹 (PTA) 是安全的. 虽然对大多数人有效,但年龄较大或症状严重的儿童可能需要更密切地监测潜在的治疗失败.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿童传染病 儿童传染病
- 深部感染 深部感染
背景情况:
- 腹腹 (PTA) 是儿童常见的深感染,传统上是通过手术治疗的.
- 仅使用抗生素治疗是针对特定儿科PTA病例的新兴替代方案.
研究的目的:
- 评估对儿科围腹 (PTA) 保守抗生素管理的疗效和安全性.
- 为了确定与治疗失败相关的风险因素,在儿童中进行非手术治疗PTA.
主要方法:
- 2004年至2014年为PTA治疗的儿科患者 (<18岁) 的回顾性观察研究.
- 分析初级治疗失败 (2周内手术/并发症),二次失败 (复发/并发症>2周) 和整体失败.
- 统计分析以确定与更高故障风险相关的因素.
主要成果:
- 在107名患者中,93名 (87%) 接受了保守的治疗,初级失效率为6.4%.
- 高龄和严重症状 (呼吸困难,三) 与失败风险增加有关.
- 整体失败率为16.1%,二次失败 (复发) 观察到入院后8年.
结论:
- 保守的抗生素管理是一种安全有效的方法,用于选择的儿科PTA病例.
- 建议对年龄较大的儿童或出现严重症状的儿童进行仔细监测.
- 长期随访表明并发症率较低,特别是在较年轻,症状较小的儿童中.
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