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Updated: Jan 17, 2026

A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells
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A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells

Published on: August 29, 2020

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作为控制人类胚胎干细胞命运的机械反应增强元件的可转移元件子集

Tongyu Sun1,2,3, Yueyuan Xu1,2,3, Nicole Angel4

  • 1Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.

Nature cell biology
|September 17, 2025
PubMed
概括

可转移元件 (TE) 响应机械信号,作为机械响应增强元件 (MREE),控制人类胚胎干细胞命运和基因表达. 这揭示了TE在细胞发育和疾病中的新作用.

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