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Updated: Jan 17, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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预测人类替代拼接的结构影响

Yuxuan Song1, Chengxin Zhang1, Gilbert S Omenn1

  • 1Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.

Genome biology
|September 17, 2025
PubMed
概括

替代拼接显著改变蛋白质结构和功能,影响翻译后修改部位. 这项研究预测了超过11000种人类异构体的结构,揭示了细胞类型特定的表达模式.

关键词:
在AlphaFold2中,我们将使用AlphaFold2.另一个替代拼接方法.异形函数是异形函数.蛋白质结构 蛋白质结构一个单细胞RNA-seqq.

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