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Updated: Jan 17, 2026

Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira
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Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira

Published on: August 14, 2021

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利用内源性I-F型CRISPR/Cas系统,有效地进行基因工程和基因抑制,在Pseudomonas chlororaphis LX24中

Yan-Fang Nie1, Sheng-Jie Yue1, Peng Huang1

  • 1State Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

ACS synthetic biology
|September 18, 2025
PubMed
概括

研究人员为Pseudomonas chlororaphis LX24开发了一个新的遗传工具包,提高了其代谢工程能力. 该系统可实现精确的基因组编辑和转录抑制,释放了农业和工业应用的潜力.

关键词:
克里斯普里是指克里斯普里.伪虫 罗拉菲斯 伪虫在内生CRISPR/Cas系统中.基因组编辑 基因组编辑限制 修改 系统限制

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