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Updated: Jan 17, 2026

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The Rigid Tube as an Alternative in Controlling the Problematic Airway
Published on: June 6, 2020
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麻醉 遗传性血管水病例的管理,该病例被计划进行气管扩张
Muharrem Uçar1, Mukadder Şanlı1, Sezai Aktürk1
1İnönü University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Malatya, Türkiye.
Turkish journal of anaesthesiology and reanimation
|September 18, 2025
概括
经过手术的遗传性血管 (HAE) 患者需要仔细监测. 预防性C1酶抑制剂可能无法预防所有手术后的发作,因此需要立即使用新鲜冷血进行治疗.
科学领域:
- 麻醉学 麻醉学
- 免疫学 免疫学 免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 遗传性血管炎 (HAE) 涉及由于C1酶抑制剂缺乏而导致布拉迪基宁的过度生产,导致反复的胀发作.
- 在全身麻醉下进行的外科手术可能会导致HAE发作,而喉水会带来显著的术后风险.
研究的目的:
- 报告1型HAE病例与气管狭窄症,需要重复硬支气管镜检查.
- 评估在患有气管狭窄症的患者手术后HAE攻击的管理.
主要方法:
- 一名患有HAE型1和气管狭窄症的患者接受了两次硬性支气管透视手术以进行气管扩张.
- 在两次手术之前都使用了预防性C1雌激酶抑制剂.
- 在重症监护室进行了术后监测.
主要成果:
- 第一次手术没有任何事件. 第二次手术后出现了面部,舌头和嘴唇胀,大约10小时后出现了.
- 该患者成功地接受了C1酶抑制剂和新鲜冷血 (FFP) 的治疗,在FFP给药后胀回归.
- 患者在症状改善后被送出院.
结论:
- 预防性C1雌激酶抑制剂可能并不总是可以预防手术后的HAE发作.
- 新鲜冷血可以有效地管理急性HAE发作.
- 建议在术后对HAE患者进行延长的重症监护病房监测 (至少48小时),以观察喉胀.
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