在多民族队列研究中,植物性饮食质量与代谢功能障碍相关的脂肪性肝病 (MASLD) 之间的关联
Darya Moosavi1, Unhee Lim2, Meredith Hullar3
1Fred Hutch Cancer Center.
Research square
|September 18, 2025
概括
健康的植物性饮食与减少肝脂肪和与代谢功能障碍相关的脂肪性肝病 (MASLD) 风险有关. 这凸显了饮食质量对于在不同人群中预防MASLD的重要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,是一个日益严重的健康问题,治疗方法很少.
- 饮食质量对MASLD风险的影响是公认的,但植物性饮食质量在不同群体中的作用需要澄清.
研究的目的:
- 调查植物性饮食模式与肝脏脂肪含量或多民族老年人中MASLD患病率之间的关联.
主要方法:
- 从肥胖现象型研究中对1598名参与者的横截面分析.
- 使用食物频率调查问卷评估植物性饮食指数 (PDI,hPDI,UPDI).
- 通过MRI和MASLD诊断测量低酒精消费者的肝脂肪;用于分析的多变量模型.
主要成果:
- 对健康植物性饮食指数 (hPDI) 的更高坚持与较低的肝脂肪和降低 MASLD 的可能性相关.
- 与其他种族/族群相比,拉丁裔和白人参与者中反向关联更强.
- 特定的hPDI成分,如坚果摄入量,显示出有益的关联,而动物脂肪摄入量与更高的肝脂肪有关.
结论:
- 坚持健康的植物性饮食与较低的肝脂肪和MASLD患病率有关,尽管存在一些种族/民族差异.
- 植物食品的质量至关重要,可以为各种人群中MASLD预防的饮食策略提供信息.
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