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Updated: Jan 17, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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通过病毒诱导的deISGylation来调节先天免疫和细胞代谢的失调

Junji Zhu, GuanQun Liu, Jielin Xu

    bioRxiv : the preprint server for biology
    |September 18, 2025
    PubMed
    概括

    在SARS-CoV-2的帕帕因类蛋白酶 (PLpro) 脱化阻碍了天生的免疫力. 抑制PLpro的活性可以增强抗病毒防御,并揭示病毒如何操纵宿主新陈代谢.

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