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Updated: Jan 17, 2026

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells
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Published on: March 3, 2015

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在PAF1和ENL/AF9 YEATS抑制之间发生的化学遗传相互作用

Paige A Barta, Leopold Garnar-Wortzel, Timothy R Bishop

    bioRxiv : the preprint server for biology
    |September 18, 2025
    PubMed
    概括

    通过降低目标基因的调节,ENL YEATS域抑制剂显示出抗白血病的作用. 然而,这种基因抑制本身并不能完全解释白血病模型中的抗增殖反应,即使具有耐药性.

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