激光治疗平色素和红斑异色素的情况:系统性审查
Nawar Tarafdar1, Marissa Joseph2,3, Chaocheng Liu4
1Western University, Schulich School of Medicine and Dentistry, London, Ontario, Canada.
概括
激光疗法,特别是Q开关的Nd:YAG,在治疗黑色皮肤色调的平色素 (LPP) 和红斑色素 (EDP) 方面具有前景. 保守的参数和组合治疗可以提高疗效和安全性.
科学领域:
- 皮肤病学 皮肤病学
- 医学美学 医学美学
- 激光疗法是一种激光疗法.
背景情况:
- 灰平原色素 (LPP) 和红斑色素 (EDP) 是黑色皮肤中常见的多颜色障碍.
- 这些疾病往往抵御常规治疗.
- 激光疗法是一个新兴的选择,其参数和安全性不清楚.
研究的目的:
- 系统地审查激光治疗LPP和EDP的疗效,激光参数和安全性.
- 综合当前关于激光治疗这些特定皮肤病的证据.
主要方法:
- 对Medline,Embase和CINAHL数据库进行了系统审查.
- 包括报告LPP或EDP激光治疗结果的研究,并对其质量进行了评估.
- 数据提取和选由两个审查员独立进行.
主要成果:
- 分析了15项涉及56名患者的研究,其中LPP更为普遍.
- 使用Q开关的Nd:YAG 1064nm激光是最常见的,达到75%的中度到完全清除.
- 皮秒和分数激光也被利用,有时与局部药物;不良事件通常是轻微的.
结论:
- 在皮肤有色素的患者中,Q开关和皮秒 Nd:YAG 激光似乎对 LPP 和 EDP 有效.
- 分数激光显示了可变的结果;保守的参数和组合疗法可以改善结果.
- 需要进行进一步的受控研究,以优化这些疾病的激光治疗方案.
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