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Updated: Jan 17, 2026

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刺激DUX4的基因定义了人类胎盘 trofhoblasts中的抗病毒防御程序

Joshua Hatterschide1,2, Liheng Yang1,2, Carolyn B Coyne1,2

  • 1Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC, USA.

The Journal of experimental medicine
|September 18, 2025
PubMed
概括

胎盘细胞使用DUX4驱动的抗病毒途径对抗疹病毒,为典型的干扰素反应提供了替代方案. 这一发现揭示了一种新的防御机制,保护胎儿免受病毒感染.

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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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