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Updated: Jan 17, 2026

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不变的TCR触发的蛋白激酶D激活介导NKT细胞发育

Eri Ishikawa1,2, Hidetaka Kosako3, Daisuke Motooka4

  • 1Department of Molecular Immunology, Research Institute for Microbial Diseases, The University of Osaka, Suita, Japan.

The Journal of experimental medicine
|September 18, 2025
PubMed
概括

蛋白激酶D (PKD) 对于不变的自然杀手T (iNKT) 细胞发育至关重要,它通过通过转录因子Ikaros将不变的T细胞受体 (iTCR) 信号与前列细胞白血病指 (PLZF) 诱导联系起来.

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