在轮班工人中,对睡眠相关图像的反应中,前额叶皮层的低活化
Hyewon Yeo1, Kyung Hwa Lee2,3, Jiyoon Shin4
1Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Brain structure & function
|September 18, 2025
概括
轮班工作者在处理与睡眠障碍相关的睡眠线索时,在前额叶皮层表现出大脑活动的改变. 这表明轮班工人 (SWs) 的注意力受损,与健康对照者 (HCs) 相比,轮班工人的反力增加.
科学领域:
- 神经科学是一个神经科学.
- 职业健康 职业健康 职业健康
- 睡眠医学 睡眠医学
背景情况:
- 轮班工作与心理健康问题有关,包括睡眠障碍和认知障碍.
- 对与睡眠相关的刺激的神经反应可能因轮班工作时间表而异.
研究的目的:
- 调查轮班工作者 (SW) 护士和健康对照者 (HCs) 之间对睡眠相关刺激的反应中大脑活动的差异.
- 评估睡眠问题和脑活动在SWs之间的关系.
主要方法:
- 功能性磁共振成像 (fMRI) 在涉及查看睡眠相关和中性图像的任务中.
- 通过问卷和睡眠日记评估主观睡眠质量.
- 目标睡眠和24小时休息活动节奏评估使用动图.
主要成果:
- 与对照人群相比,轮班工作者在观看与睡眠有关的图片和中性图片时,在背中中前额皮层 (DMPFC) 和侧面前额皮层 (LPFC) 中的激活明显较低.
- DMPFC活动与主观睡眠问题 (失眠,疲劳) 有负相关性.
- LPFC活动与24小时休息活动节律参数相关.
结论:
- 在SW中前额叶皮层激活的减少可能表明注意力控制睡眠的减少和反的增加.
- 这些发现阐明了SWS中睡眠相关问题的神经生物学机制.
- 结果可能会为轮班工人心理健康的干预提供信息.
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