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在一个大规模的全县安全网电视网查计划中,急性角度关闭的发生率

Tracy Z Lang¹, Benjamin Y Xu¹, Zhiwei Li²

¹Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles.

JAMA ophthalmology

|September 18, 2025

概括

药理学瞳孔扩张在眼科检查中是安全的,急性视角关闭 (AAC) 的风险非常低 (0.002%). 这项研究验证了使用ICD代码来识别扩张后的AAC病例.

科学领域:

眼科医生眼科眼科
公共卫生公共卫生
医疗信息学医疗信息学

背景情况:

药理学瞳孔扩张对于诊断眼睛疾病至关重要.
担心引发急性角关闭 (AAC),眼科紧急情况,往往导致避免扩张.
验证用于识别AAC病例的方法对于患者安全和研究至关重要.

研究的目的:

为了确定药理学瞳孔扩张后AAC的发生率.
评估国际疾病分类 (ICD) 代码在扩张后识别AAC病例时的准确性.
在一个大规模的糖尿病视网膜病变查计划中评估扩张的安全性.

主要方法:

对患者进行了回顾性队列研究,这些患者参加了Teleretinal糖尿病视网膜病变查 (TDRS) 计划.
在扩展后的特定时间框架内使用ICD代码和程序代码识别潜在的AAC案件.
手动医疗记录审查用于AAC病例验证和数据提取.

主要成果:

在84,008名患者身上,共进行了168,796次扩张.
扩张后发生了四例确诊的AAC病例,导致每次扩张的发病率为0.002%.
发现AAC的风险很低,特别是在服务于多样化人口的大量查计划中.

结论:

药理学瞳孔扩张表明,即使在多样化,大体积查环境中,诱导急性角度闭合的风险很低.
这些发现支持瞳孔扩张用于查眼病的整体安全性.
关于AAC扩张风险的禁忌的进一步讨论是合理的.

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