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Updated: Jan 17, 2026

Generation of Topically Transgenic Rats by In utero Electroporation and In vivo Bioluminescence Screening
08:44

Generation of Topically Transgenic Rats by In utero Electroporation and In vivo Bioluminescence Screening

Published on: September 24, 2013

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破坏整合器复合体子单元INTS6会导致神经发育障碍,并损害神经发生和突触发育

Xiaoxia Peng1,2, Xiangbin Jia1,2, Hanying Wang1,2

  • 1Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.

The Journal of clinical investigation
|September 18, 2025
PubMed
概括

集成器综合体子单元INTS6与神经发育障碍 (NDD) 有关. INTS6变种导致发育延迟和认知缺陷,但CDK9抑制剂显示出治疗前景.

关键词:
遗传变异是一种遗传变异.遗传学 是一个遗传学.神经科学是一个神经科学.

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Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders07:43

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