Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

783
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
783
Information Processing Approach01:30

Information Processing Approach

522
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
522

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

TRUE-MOGAD Score: A Novel Scoring System to Identify MOGAD Among Positive MOG-IgG Test Results.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

Impact of multiple sclerosis disease-modifying therapies on chronic lesion tissue expansion.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach.

JMIR research protocols·2026
Same author

Education Research: The Future of Child Neurology Residency Training: The Perspective of a Child Neurology Society Task Force.

Neurology. Education·2026
Same author

A Case of Persistent Ataxia and Atypical Brain Lesions: From the National Multiple Sclerosis Society Case Conference Proceedings.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

Application of the 2024 McDonald Criteria in Individuals With Nonspecific Symptoms or Incidental Imaging Findings in a Multicenter Study.

Neurology·2026

相关实验视频

Updated: Jan 17, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.6K

2年以上儿童多发性硬化症患者的认知功能

Kimberly A O'Neill1, Leigh Charvet1, Michael Waltz2

  • 1Department of Neurology, NYU Grossman School of Medicine, New York.

Neurology
|September 18, 2025
PubMed
概括

大多数患有儿科多发性硬化症 (MS) 的儿童在两年内保持了稳定的认知功能,类似于健康的同龄人. 然而,一个小组的处理速度有所下降,这凸显了儿童多发性硬化症患者认知健康监测的必要性.

更多相关视频

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.8K
Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
07:35

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Published on: December 29, 2023

1.9K

相关实验视频

Last Updated: Jan 17, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.6K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.8K
Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
07:35

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Published on: December 29, 2023

1.9K

科学领域:

  • 神经学 神经学
  • 儿科 儿科 儿科
  • 认知科学 认知科学

背景情况:

  • 儿童多发性硬化症 (MS) 影响儿童的神经和认知发育.
  • 儿童多发性硬化症认知功能的长度研究有限.
  • 认知障碍是儿童多发性硬化症的一个已知的问题.

研究的目的:

  • 纵向评估两个多年多发性硬化症儿童的认知功能.
  • 为了比较儿科MS患者的认知变化与年龄相匹配的健康对照 (HCs).
  • 为了研究儿童MS的认知变化,与早期发病的MS的成年人相比.

主要方法:

  • 在七个美国地区招募了三个队列:儿科MS,儿科HC和成人MS患者.
  • 在基线和随访时使用Cogstate简要电池 (CBB) 和MS国际简要认知评估 (BICAMS).
  • 分析了复合z-score和个体认知指标的变化,计算可靠的变化指数 (RCI).

主要成果:

  • 儿科MS和儿科HC之间CBB复合z-score变化没有显著差异 (p=0.113).
  • 儿童多发性硬化和成人多发性硬化组也显示出类似的认知变化 (p=0.987).
  • 虽然80%的儿科MS患者情况稳定或有所改善,但19.7%的认知能力下降,而对照组5.1% (p=0.022).

结论:

  • 大多数儿科MS患者在两年内表现出稳定的认知功能.
  • 儿科MS的认知变化在很大程度上与健康儿科对照组的认知变化相当.
  • 儿科MS患者的一个子集可能会随着时间的推移而经历认知处理速度的下降.