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Updated: Jun 29, 2026

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection
09:45

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection

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一个启用NanoLock的,基于Craspase的战略,用于高度敏感的RNA检测.

Yumeng Xiao1, Junyu Chen1, Xincan Hou1

  • 1State Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.

Nucleic acids research
|September 18, 2025
PubMed
概括

一个新的基于CRISPR的诊断平台提供了快速,无放大RNA检测. 这项名为Craspase-NanoLock-Csx30 (CNC) 的技术在几分钟内实现了高灵敏度的病毒RNA检测.

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MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as A Novel Detection and Quantification Method09:06

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...