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Updated: Jan 17, 2026

Examination of Proteins Bound to Nascent DNA in Mammalian Cells Using BrdU-ChIP-Slot-Western Technique
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Published on: January 14, 2016

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INO80/SWR重塑器通过BRD2和染色体景观调节Pol II转录

Meitong Liu1, Qiqin Xu1, Hui Wang1,2

  • 1State Key Laboratory of Gene Function and Modulation Research, Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, Beijing Advanced Center of RNA Biology (BEACON), School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.

Nucleic acids research
|September 18, 2025
PubMed
概括

INO80/SWR重塑剂通过影响BRD2染色体结合来调节基因表达. 这项研究确定了它们的直接目标,并澄清了它们在Pol II转录中的作用,这对发育和疾病至关重要.

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