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癌症基因组突变影响蛋白质结合和DNA修复,可能与基因组不稳定性有关

Daniel Espiritu1, Yiru Sheng2, Yunhui Peng3

  • 1Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON K7L 2V6, Canada.

Nucleic acids research
|September 18, 2025
PubMed
概括

基因组突变通过改变基因组调节来影响癌症的发展. 这项研究确定了包括H4在内的特定基因组突变,通过影响DNA修复相互作用来驱动癌症.

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