产前母亲的压力和长期的神经发育结果:一个叙事审查
Dimitris Baroutis1, Ioanna Myrto Sotiropoulou1, Rafail Mantzioros1
11st Department of Obstetrics & Gynecology, Alexandra Hospital, 68993 National and Kapodistrian University of Athens , Athens, Greece.
Journal of perinatal medicine
|September 18, 2025
概括
怀孕期间母亲的压力与儿童的长期神经发育问题有关,影响认知和行为. 早期干预和母亲心理健康支持是缓解这些风险的关键.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 孕产妇健康 孕产妇健康
背景情况:
- 产前母亲的压力显著影响胎儿发育和后代的神经发育.
- 了解这些影响对于围产期护理策略至关重要.
- 考察了各种各样的压力因素,从心理痛苦到创伤.
研究的目的:
- 审查产前母亲压力对后代的长期后果.
- 探索将母亲压力与神经发育结果联系起来的生物机制.
- 综合流行病学,神经生物学和临床研究的证据.
主要方法:
- 流行病学,神经生物学和临床研究的叙述性综述.
- 对各种母亲压力因素及其与儿童结果的关联进行分析.
- 讨论包括HPA轴,表观遗传学和神经炎症在内的生物途径.
主要成果:
- 怀孕期间母亲的压力与儿童神经发育挑战的风险增加密切相关.
- 后代的结果包括执行功能缺陷,焦虑,抑郁和精神疾病易感性.
- 影响是由暴露时间,遗传学和产后环境调节的.
结论:
- 产前压力对儿童的神经发育构成重大风险,影响认知,情感和行为领域.
- 方法上的局限性需要纵向的,基于生物标志物的研究和干预研究.
- 将母亲心理健康支持纳入产前护理是一个有前途的战略.
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