基因组多样性和与表面水中的Listeria monocytogenes存在相关的环境因素
Magaly Toro1, Daniel Weller2, Camila Solar3
1Joint Institute for Food Safety and Applied Nutrition/Center for Food Safety & Security Systems, University of Maryland, College Park, MD, 20740, USA.
The Science of the total environment
|September 18, 2025
概括
在智利的灌水中检测到Listeria monocytogenes,其流行率因地点和季节而异. 基因分析揭示了多样化的菌株,其中一些具有毒性和耐药性基因,突出显示了环境持久性风险.
科学领域:
- 环境微生物学环境微生物学
- 食品安全 食品安全
- 公共卫生 公共卫生
背景情况:
- 李斯特菌 (Listeria monocytogenes) 构成一个重要的食物传播疾病风险.
- 灌水是传染病原体向作物传播的潜在载体.
- 了解L. monocytogenes在水中的流行程度对于降低风险至关重要.
研究的目的:
- 在智利灌水中检测和描述L. monocytogenes.
- 评估与L. monocytogenes污染相关的流行率,遗传多样性和风险因素.
- 为减少食源性疾病风险的战略提供信息.
主要方法:
- 在一年内,每月从智利四个流域的120个地点收集1050个水样.
- 检测和对L. monocytogenes分离物的遗传特征.
- 影响病原体存在的环境因素 (水类,月份,流域,pH,季节) 的分析.
主要成果:
- L. monocytogenes 的流行率在流域中从15%到25%不等,受水类型,季节和pH的影响.
- 基因分析确定了跨地区和时间的克隆分离物,主要是血清组IVb.
- 病毒性基因 (LIPI1) 是常见的;抗菌素耐药性基因 (mefA, msrD) 是罕见的.
- 在L. monocytogenes和沙门氏菌存在之间没有发现任何关联.
结论:
- 智利的淡水环境拥有基因多样性的L. monocytogenes菌株.
- 环境持久性和水库可能解释了菌株的传播.
- 需要改进监测和控制策略,以减轻与污染灌水相关的公共卫生风险.
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