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Updated: Jan 17, 2026

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
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与单一原发性癌症相比,口腔多重原发性癌症中的免疫和HPV景观

Xuan Zhou1, Jianyun Zhang1, Yue Lou2

  • 1Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China; Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), Beijing, China.

Oral oncology
|September 18, 2025
PubMed
概括

多重原发性口腔癌 (MPCs) 与单一原发性癌 (SPCs) 相比,显示出一个独特的免疫微环境. MPCs具有较少的淋巴细胞和更多的巨细胞,独立于HPV感染,表明独特的发病因子.

关键词:
在HPV中,HPV是HPV.免疫微环境是一个微环境.免疫组织化学染色口腔多重原发性癌症口腔多重原发性癌症状细胞癌瘤是一种状细胞癌.

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