在用于复发性呼吸道乳头瘤病的光动力疗法后,复发性损伤分布
Yufei Pan1, Huili Huang2, Ke Wu2
1School of Medicine, Southeast University, 87 Dingjiaqiao, Hunan Road, Nanjing 210009, Jiangsu, China; Department of Otolaryngology-Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China; Nanjing Medical Key Laboratory of Laryngopharynx-Head & Neck Oncology, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
Photodiagnosis and photodynamic therapy
|September 18, 2025
概括
复发性呼吸道乳头瘤 (RRP) 的光动力学疗法 (PDT) 显示在上衣和后喉区域的复发率更高. 在RRP的PDT治疗后,in-situ复发比异位复发更为常见.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 医疗技术 医疗技术 医学技术
背景情况:
- 由于传统手术的复发率很高,复发性呼吸道乳头瘤 (RRP) 是一个挑战.
- 光动力疗法 (PDT) 为RRP提供了一个区域清除策略.
- 在PDT后的RRP复发的解剖分布需要进一步阐明.
研究的目的:
- 评估RRP的PDT后复发性病变的解剖分布.
- 为了确定特定的喉区域,在PDT后复发率较高.
- 为RRPPDT治疗方案的优化提供信息.
主要方法:
- 对43名接受PDT (2021-2024) 治疗的RRP患者的回顾性分析.
- 每月进行喉腔镜检查,以追踪复发.
- 评估病变分布在11个解剖学区域,并比较in-situ和异位复发.
主要成果:
- 视膜表达了最高的相对复发率 (75.00%).
- 后喉区域的复发率较高 (63.16%) 与前区域 (50.00%) 相比.
- 现场复发的发生率明显高于异位复发的发生率 (P < 0.001).
结论:
- 在RRP的PDT后,在解剖区域之间存在复发率的显著变化.
- 表皮和后部区域更容易发生复发.
- 现场复发是使用PDT治疗的RRP中占主导地位的模式.
相关概念视频
01:27Pneumothorax-II
921
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
921
01:30Skin Cancer
5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K