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伊卡里西德II通过抑制巨细胞极化和抑制cGAS-STING通路来改善缓慢过渡性便秘

Ziying Jiang1, Fangxu Yin1, Yaqian Ping1

  • 1Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.

European journal of pharmacology
|September 18, 2025
PubMed
概括

伊卡里西德II (ICS II) 通过减少炎症和保护神经,有效治疗缓慢过渡性便秘 (STC). 它通过抑制cGAS-STING通路和降低M1巨细胞极化而起作用.

关键词:
肠道神经系统 肠道神经系统伊卡里西德二号 伊卡里西德二号巨细胞的两极分化缓慢过渡性便秘 缓慢过渡性便秘cGAS-STING 信号通道的信号通道

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