黄类药物摄入量和结石:基于暴露基的横截面研究
Yuan Gong1, Yuanyuan Yang1, Lintao Miao1
1Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
The Journal of nutritional biochemistry
|September 18, 2025
概括
饮食中摄入弗拉万,特别是来自像纳灵宁这样的来源,可能会降低结石的风险. 这项研究发现了J形关系,表明适度饮食对脏健康最有益.
科学领域:
- 营养科学 营养科学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 饮食流行病学 饮食流行病学
背景情况:
- 结石是一种普遍的健康问题.
- 饮食因素显著影响结石的形成.
- 黄酸是具有潜在健康益处的植物化合物.
研究的目的:
- 为了研究饮食中的黄酸盐摄入量与结石风险之间的关联.
- 探索特定的黄类子组的剂量反应关系.
主要方法:
- 来自国家健康和营养检查调查 (NHANES) 数据的分析.
- 利用饮食研究的食品和营养数据库 (FNDDS) 进行饮食摄入.
- 包括9033名没有结石的参与者和985名结石的参与者.
主要成果:
- 在弗拉万摄入量和结石风险 (P < .001) 之间观察到J形关系.
- 纳灵宁与结石风险有负面关联.
- 赫斯佩雷丁还表现出与结石风险的J型关联.
结论:
- 黄的消费可能会对结石产生保护作用.
- 像纳灵宁和赫斯佩雷丁这样的特定黄类药物需要进一步研究石预防.
- 专注于黄的饮食修改可能是管理结石风险的策略.
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