自然植物多糖体通过"肠道微生物群-代谢物-宿主"轴驱动多维代谢平衡
Li Zhang1, Xin Chen2, Jiali Li1
1School of Pharmacy, Naval Medical University, Shanghai, 200433, China; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
International journal of biological macromolecules
|September 18, 2025
概括
自然植物多糖类作为益生菌,调节肠道微生物群以改善宿主新陈代谢. 本综述详细介绍了这些化合物如何调节有益细菌和代谢物,影响脂肪酸和氨基酸途径对代谢健康的影响.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 肠道微生物群是宿主代谢健康的关键因素.
- 自然植物多糖具有多样化的结构和益生菌性质.
- 肠道微生物群的失调与代谢疾病有关.
研究的目的:
- 系统地审查天然植物多糖体,肠道微生物群和宿主代谢之间的相互作用.
- 阐明多糖对宿主代谢途径的影响机制.
- 为代谢性疾病的营养干预提供指导.
主要方法:
- 系统的文献审查.
- 分析涉及肠道微生物群调节的机制.
- 检查多糖对宿主代谢过程的影响.
主要成果:
- 自然植物多糖选择性地促进有益的肠道细菌.
- 多糖类通过微生物代谢产物影响宿主代谢.
- 确定了调节脂肪酸,胆酸和氨基酸代谢的特定机制.
结论:
- 自然植物多糖对于维持肠道微生物群平衡和宿主代谢健康至关重要.
- 了解这些相互作用为精密营养提供了基础.
- 这项研究支持预防和治疗慢性代谢疾病.
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