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适度至剧烈的体力活动与背部疾病风险之间的剂量反应关系:一项大型加速测试研究

Rubén López-Bueno¹, Lars Louis Andersen², Laura López-Bueno³

¹Faculty of Health Sciences, Public University of Navarra, Pamplona, Spain.

Journal of the American Medical Directors Association

|September 18, 2025

概括

适度至剧烈的体力活动 (MVPA) 可以降低背部疾病的风险. 腰部疾病的最佳每周MVPA是400分钟,背部疾病的最佳每周MVPA是670分钟. 较高的MVPA可能有利于宫疾病,但可能会损害腰部疾病.

科学领域:

流行病学流行病学
公共卫生公共卫生
运动医学运动医学

背景情况:

肌肉骨疾病,包括腰部疾病 (LBDs),背部疾病 (DDs) 和宫疾病 (CDs),是严重的公共卫生问题.
身体活动被认为是维持肌肉骨健康的关键因素,但不同程度的中度至剧烈身体活动 (MVPA) 与这些疾病的风险之间的具体关联需要进一步阐明.

研究的目的:

调查不同程度的中度至剧烈体力活动 (MVPA) 与腰部疾病 (LBD),背部疾病 (DD) 和宫疾病 (CD) 的发生率之间的剂量反应关联.

主要方法:

采用前性队列研究设计,利用英国生物库中的74,191名参与者的数据以及加速度计数据.
参与者被跟踪了7.9年的中位数,以确定LBDs,DDs和CDs的事件病例.
限制立方线和考克斯回归模型被用来分析MVPA与这些疾病的风险之间的关联.

主要成果:

该研究确定了MVPA的特定最佳每周持续时间,以减少不同脊柱疾病的风险.
对于LBDs,最优的MVPA剂量是每周400分钟 (HR,0.68;95%CI,0.59-0.78).
对于DDs,最佳的MVPA剂量是每周670分钟 (HR,0.53;95%CI,0.42-0.67).
对于CDs,观察到一个显著的反向关联,在较高的MVPA水平 (例如,1265分钟/周,HR,0.53;95%CI,0.28-0.99) 中观察到最佳益处.

结论:

虽然每天大约一小时的MVPA可能对一般的背部健康有益,但最佳的MVPA剂量取决于具体的脊柱区域.
较高的MVPA水平可能为宫疾病提供额外的好处,但可能会增加腰部疾病的风险.
监测和达到最佳的MVPA水平可能是预防脊髓疾病的有价值策略,建议进行进一步的研究和干预来证实这些发现.

关键词:

运动运动运动.慢性疾病慢性疾病流行病学流行病学疼痛疼痛疼痛疼痛

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