[肺癌在中国和全球的流行病学特征]
Y M Ding1, B J Jiang1, H Q Tao1
1School of Public Health, Nanjing Medical University, Nanjing 211166, China Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China.
Zhonghua zhong liu za zhi [Chinese journal of oncology]
|September 18, 2025
概括
全球肺癌发病率和死亡率很高,特别是在中国,与人类发展指数 (HDI) 有很强的相关性. 迫切需要有针对性的预防策略,特别是在高风险人群中,因为中国面临着不成比例的疾病负担.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 肺癌仍然是全球癌症发病率和死亡率的主要原因.
- 在全球不同地区,人口统计和发展水平之间,肺癌负担存在显著差异.
- 了解这些流行病学模式对于制定有效的预防和控制策略至关重要.
研究的目的:
- 分析全球和中国肺癌发病率和死亡率的现状和趋势.
- 调查人类发展指数 (HDI) 与肺癌率之间的关联.
- 为改进中国的肺癌预防战略提供基于证据的见解.
主要方法:
- 数据是从GLOBOCAN 2022数据库中提取的.
- 年龄标准化发病率 (ASIR) 和年龄标准化死亡率 (ASMR) 用Segi的世界标准人口计算.
- 根据地区,年龄,性别和HDI分析了流行病学模式,并进行了统计分析,包括线性回归和斯皮尔曼相关性.
主要成果:
- 在2022年,全球肺癌发病率为248万例,死亡率为182万例,ASIR为23.6/100,000,ASMR为16.8/100,000.
- 肺癌负担与HDI有显著的相关性 (ASIR:r=0.79,ASMR:r=0.74,P<0.001). 肺癌负担与HDI有显著的相关性 (ASIR:r=0.79,ASMR:r=0.74,P<0.001).
- 中国的病例为106万例,死亡人数为730万例,超过全球平均水平;预测显示,到2050年,病例将大幅增加.
结论:
- 肺癌负担在人口统计和发展水平上表现出显著的异质性,与HDI密切相关.
- 中国承受着不成比例高的肺癌负担,这强调了加强预防工作的必要性.
- 针对高风险人群,迫切需要针对性的干预措施,以减轻肺癌日益严重的影响.
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