[肝癌在中国和全球的流行病学特征]
1Department of Etiology, Qidong People's Hospital/Qidong Liver Cancer Institute/Affiliated Qidong Hospital of Nantong University, Qidong 226200, China.
Zhonghua zhong liu za zhi [Chinese journal of oncology]
|September 18, 2025
概括
肝癌的发病率和死亡率在全球范围内各不相同,男性和老年人的发病率更高. 预计到2050年,全球肝癌负担将大幅增加.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 癌症研究 癌症研究
背景情况:
- 肝癌代表着一个重要的全球健康挑战,具有不同的流行病学模式.
- 了解发病率,死亡率和趋势对于有效的预防和控制策略至关重要.
研究的目的:
- 分析全球和中国肝癌的发病率,死亡率和流行病学趋势.
- 为全球肝癌预防和控制工作提供数据参考.
主要方法:
- 利用了GLOBOCAN 2022肝癌发病率,死亡率和趋势数据的数据库.
- 使用斯皮尔曼测试和Joinpoint回归分析来评估与HDI和趋势的相关性.
- 在不同地区,年龄组和性别之间比较流行病学特征.
主要成果:
- 在2022年,全球肝癌病例为866,000例,死亡人数为759,000例;中国报告了368,000例和317,000例死亡.
- 在所有地区,在男性和老年人中观察到更高的发病率和死亡率.
- 肝癌发病率和死亡率与人类发展指数 (HDI) 有负相关性.
- 趋势表明,东亚国家的发病率下降,但在美国的发病率增加.
- 预测表明,到2050年,全球肝癌病例和死亡人数将大幅增加.
结论:
- 在全球范围内,肝癌负担存在显著差异,受地区,性别和年龄的影响.
- 较低的人类发展指数 (HDI) 与较高的肝癌发病率和死亡率有关.
- 预计肝癌的增加需要加强全球预防和控制策略.
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