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对良性前列腺阻塞的最小侵入性手术治疗的功能性和性结果的系统审查和聚合分析
Antonio Franco1, Francesco Ditonno2, Celeste Manfredi3
1Department of Urology, Sant' Andrea Hospital, Sapienza University, Rome, Italy.
European urology
|September 18, 2025
概括
良性前列腺阻塞的最小侵入性外科治疗 (MIST) 提供有效的症状缓解和保持性功能. 这些程序在国际前列腺症状评分和生活质量方面显著改善,并发症率低.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 良性前列腺阻塞管理管理
背景情况:
- 良性前列腺阻塞 (BPO) 是老年男性常见的疾病.
- 药物治疗可以缓解症状,但会影响性功能.
- 最少侵入性外科治疗 (MISTs) 旨在改善症状,同时保持性健康.
研究的目的:
- 系统地评估BPO各种MIST的结果.
- 将MIST与现有治疗方法的疗效和安全性进行比较.
- 建议对MISTs.进行程序成功的标准化定义.
主要方法:
- 在PubMed,Scopus,Web of Science和Cochrane图书馆数据库中进行系统的文献搜索.
- 包括对MIST的随机对照试验和前性研究 (Rezūm,UroLift,iTind,TPLA,Optilume).
- 术后和功能结果的聚合分析,包括偏差风险评估和证据分级的确定性.
主要成果:
- 大多数MIST在12个月后在国际前列腺症状评分 (IPSS) 和最大流量 (Qmax) 中显著改善.
- 观察到射率低 (0-5%) 和并发症/再治疗率低.
- 提出的成功定义包括IPSS,Qmax和QoL的改善≥50%,性功能得到保护,没有重大并发症.
结论:
- MIST在管理BPO症状和改善生活质量方面是有效的.
- 这些程序显示出良好的安全性,特别是在性功能保护方面.
- 程序成功的拟议定义为评估MIST结果提供了一个基准.
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