相关实验视频

Updated: Jan 17, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

14.4K

生物灵感转移甲基化通过光活性试剂启用

Ding Zhang1,2, Weiqiu Liang3, Zhihan Zhang4

  • 1School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen, Guangdong, China.

Nature communications
|September 18, 2025
PubMed
概括

研究人员开发了一种新的仿生试剂,用于挑战激进甲基化反应. 这种光活性工具增强了对甲基转移的控制,使复杂分子中的选择性C-H甲基化成为可能.

更多相关视频

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling08:34

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling

Published on: December 18, 2017

7.0K
Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

9.5K

相关概念视频

Phase II Reactions: Methylation Reactions01:17

Phase II Reactions: Methylation Reactions

Methylation is a phase II biotransformation process involving the attachment of a methyl group to a substrate. Enzymes known as methyltransferases orchestrate this reaction.
The mechanism of methylation unfolds in two stages. The first stage sees a methyltransferase enzyme facilitating the transfer of a methyl group from S-adenosylmethionine (SAM) to the substrate, forming S-adenosylhomocysteine (SAH). The second stage involves further metabolism of SAH into homocysteine, which can be recycled...
680