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人类MRE11-RAD50-NBS1对DNA断裂传感的结构基础及其通过端粒因子TRF2的调节

Yilan Fan1, Filiz Kuybu1, Hengjun Cui1

  • 1Gene Center, Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor Lynen Straße 25, 81377, Munich, Germany.

Nature communications
|September 18, 2025
PubMed
概括

该MRE11-RAD50-NBS1 (MRN) 复合体检测DNA双链断裂 (DSBs) 使用类似的结构. 在端粒上结合TRF2调节MRN.

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