心率对Fontan循环中的血液动力学的影响
Aya Miyazaki1,2,3, Yoshifumi Fujimoto4, Yasumi Nakashima5,6
1Department of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan. ayamiya@pc4.so-net.ne.jp.
在Fontan循环的成年人中建立了标准心率 (HR). 在活动期间更高的HR与更好的血液动力学相关,这表明HR管理对Fontan患者至关重要.
科学领域:
- 心脏病学 心脏病学
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 标准心率 (HR) 和它对Fontan循环的影响还没有得到很好的定义.
- 喷泉循环需要仔细的血液动力学管理,HR是关键因素.
研究的目的:
- 为了确定Fontan循环的成年人的标准心率值.
- 在Fontan患者中调查心率和血液动力学参数之间的关系.
- 为了比较带有心脏起器 (PM) 和没有心脏起器 (PM) 的患者之间的心率概况.
主要方法:
- 在59名没有心脏起器的成年人中评估HR和血液动力学参数.
- 与15名带有心脏起器的患者进行了比较.
- 在各种活动中测量HR,包括睡眠,休息,日常活动和运动 (CPX).
主要成果:
- 已确立的Fontan循环的成年人标准HR值:~50 bpm (睡眠),~75 bpm (仰卧),~80 bpm (霍尔特平均),~85 bpm (坐着),~140 bpm (最大每日活动),~165 bpm (运动).
- 运动期间更高的HR和运动和睡眠之间更大的HR变化 (ΔHR) 与有利的血液动力学有关.
- 与非起器组相比,起器组在坐着以外的活动中显示出更高的睡眠HR和更低的HR.
结论:
- 身体活动期间心率升高可能会支持最佳的Fontan循环.
- 在Fontan患者中植入心脏起器患者应考虑增加HR活动,狭窄QRS持续时间和心房同步的设置.
更多相关视频
06:29Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
Published on: May 2, 2025
07:49Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
Published on: July 21, 2023
相关概念视频
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Pathophysiology of Cardiac Performance
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Blood Flow
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
