高强度运动改善了类风湿性关节炎患者的多维疲劳和与健康有关的生活质量:一项随机对照研究
Annelie Bilberg1,2, Jan Bjersing3,4, Mats Börjesson5,6
1Institution of Neuroscience and Physiology, Section of Health and Rehabilitation, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. annelie.bilberg@rheuma.gu.se.
Arthritis research & therapy
|September 19, 2025
概括
高强度间歇训练 (HIIT) 和力量炼显著减少了多维疲劳,改善了类风湿性关节炎 (RA) 患者的生活质量. 这些好处持续了12个月,证明了长期的影响.
科学领域:
- 类风湿病学 类风湿病学
- 运动生理学 运动生理学
- 临床试验 临床试验
背景情况:
- 风湿性关节炎 (RA) 通常会导致长时间的疲劳,影响生活质量.
- 建议在RA疲劳管理中进行体力活动,但最佳的运动类型和剂量仍然不清楚.
- 这项研究研究了高强度间歇训练 (HIIT) 和力量炼对RA症状的影响.
研究的目的:
- 评估12周监督HIIT和力量炼计划对RA患者疲劳,睡眠,情绪,疼痛和生活质量的影响.
- 为了比较HIIT和力量炼对一般身体活动建议的影响.
主要方法:
- 87名RA参与者被随机分配到干预组 (HIIT和力量炼) 或对照组 (一般体力活动建议).
- 评估包括多维疲劳库存 (MFI-20),匹兹堡睡眠质量指数 (PSQI),医院焦虑和抑郁量表 (HADS),疼痛 (VAS) 和与健康有关的生活质量 (VAS-全球) 在基线,3个月,6个月和12个月.
- 使用DAS28-ESR测量疾病活性,使用ANCOVA和混合模型重复测量进行统计分析.
主要成果:
- 干预组在3个月后在一般和身体疲劳,活动减少,动机减少和整体生活质量方面显著改善.
- 这些改善,特别是在身体疲劳和生活质量方面,在6个月后仍然存在.
- 在12个月后,与对照组相比,干预组的身体疲劳,抑郁情绪,疼痛和生活质量明显改善.
结论:
- 12周的高强度运动干预有效减少了多维疲劳,并改善了RA患者的健康相关生活质量.
- 对疲劳和生活质量的积极影响表明持久性,在整个12个月的随访期间持续存在.
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