细菌菌株的抗生素耐药性模式在儿童尿路感染 (UTI) 中
Mehrnoush Afsharipoor1, Fatemeh Sadat Mir Rashidi1, Fatemeh Dehghan1
1Department of Pediatrics, School of Medicine, Imam Khomeini Hospital, Jiroft University of Medical Sciences. Jiroft, Iran.
Infectious disorders drug targets
|September 19, 2025
概括
儿童尿路感染 (UTI) 显示出高抗生素耐药率,大肠杆菌是最常见的病原体. 需要紧急监测,以对抗儿童的多药耐药细菌.
科学领域:
- 儿童传染病 儿童传染病
- 微生物学 微生物学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 尿路感染 (UTI) 在儿童中很常见,抗菌素耐药性增加使治疗复杂化.
- 大肠杆菌 (Escherichia coli) 是儿科尿路感染的主要尿病原体,对安皮西林,塞菲西姆和塞夫triaxone 等常见抗生素具有很高的耐药性率 (50-70%).
研究的目的:
- 为了研究在吉罗夫特市从患有尿路感染的儿科患者中分离出来的细菌菌株的频率和抗生素耐药性模式.
主要方法:
- 在2022-2023年间对113名14岁以下患有尿路感染的儿童进行了横截面研究.
- 从医疗记录中收集的数据,并使用SPSS (版本 22) 进行分析.
主要成果:
- 大肠杆菌是最常见的病原体 (63.7%),其次是肠杆菌 (19.4%).
- 观察到令人担忧的抗生素耐药性,在一些菌株中对安皮西林和塞菲西姆有100%的耐药性.
结论:
- 儿童尿路感染中抗生素耐药性的高水平需要持续监测.
- 了解区域性耐药性模式对于优化抗生素管理和打击多抗药性病原体至关重要.
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