普兰托西亚尼丁B2通过调节星球细胞xCT/GSH/GPX4轴来缓解cuprizone诱导的脱叶林化

Jian Liu1,2, Yan-Xia Hou1, Ying Chen1

  • 1Research Center of Neurobiology, the Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.

PubMed
概括

在多发性硬化症的小鼠模型中,Proanthocyanidin B2 (PCB2) 通过调节星球细胞中的xCT/GSH/GPX4通路,有效降低了脱髓化. 这表明PCB2可能是MS治疗的有前途的治疗剂.