核心到皮肤温度梯度和毛细血管补充时间的实用性,用于确定感染性休克患者的预后:一项前性观察性研究
Sujeet Rai1, Arti Goutam1, Manoj Tripathi1
1Department of Anesthesia and Critical Care, Dr. RMLIMS, Lucknow, India.
International journal of critical illness and injury science
|September 19, 2025
概括
核心至皮肤温度梯度 (CSTG) 有效预测了败血症休克患者的8天死亡率. 这种温度梯度显示出更高的预后准确性比毛细血管补充时间 (CRT) 对于败血性休克的结果.
科学领域:
- 关键护理医学 关键护理医学
- 生理学 生理学 生理学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 败血性休克涉及复杂的微循环变化,影响器官输液.
- 核心至皮肤温度梯度 (CSTG) 和毛细血管补充时间 (CRT) 等临床指标反映了微循环状态.
- 了解预后标志物对于管理败血症休克至关重要.
研究的目的:
- 评估CSTG在预测败血症休克8天死亡率方面的预后意义.
- 为了比较CSTG与CRT的预测性表现,以预测败血症休克的结果.
- 探索CSTG与败血症休克中的其他临床参数之间的关联.
主要方法:
- 一项前性观察性研究,涉及54名败血症休克患者.
- 使用红外热谱和食道温度探针测量CSTG.
- 将CSTG与CRT进行比较,平均动脉压,乳酸,尿量和血管压缩剂的使用.
主要成果:
- 在CSTG和8天死亡率之间发现了显著的相关性.
- 与幸存者相比,死亡的患者的平均CSTG (1.21°C差异) 更高.
- CSTG (>7°C) 在预测8天死亡率方面表现出更高的灵敏度 (87.2%),而不是CRT (>4秒,在6小时时25.6%的灵敏度).
结论:
- CSTG是一个可靠的预测器8天死亡率在败血症休克.
- 与CRT相比,CSTG在败血性休克患者中提供了更好的预后能力.
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