圆度指数和胆结石疾病之间的关联:NHANES 2017-2020年间的一项横截面研究
Jie Wang1, Songsheng Zhou1, Na He1
1Department of Hepatobiliary and Pancreatic Surgery, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang 315048, China.
Preventive medicine reports
|September 19, 2025
概括
圆度指数 (C指数) 与胆结石病 (GSD) 患病率有积极联系. 较高的C指数值可能表明患上胆结石的风险增加,表明其作为临床标记物的潜力.
科学领域:
- 医学科学 医学科学 医学科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 圆度指数 (C指数) 是一种与各种疾病相关的公认指标.
- 之前没有研究过C指数和胆结石病 (GSD) 之间的关系.
研究的目的:
- 探索圆度指数与胆结石病的患病率之间的潜在关联.
- 为了评估与其他人类指数相比,GSD的C指数的预测性能.
主要方法:
- 利用了2017-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 员工调查加权的多变量逻辑回归和受限立方线回归分析.
- 进行了接收器操作特征 (ROC) 曲线分析,以比较预测能力.
主要成果:
- 在3626名参与者中,C指数和GSD患病率之间发现了显著的积极关联.
- 每一个标准偏差增加的C指数与GSD几率上升30%相关 (OR = 1.30).
- 与腰部和部比率 (WHR) 相比,C指数显示了GSD的优越预测能力,并且与体重指数 (BMI) 相当.
结论:
- 这项研究确立了圆度指数和胆结石疾病患病率之间的显著正相关性.
- 圆度指数显示了作为一种有价值的临床标志物,用于早期检测胆结石的潜力.
相关概念视频
Gallbladder
2.0K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
2.0K
Diseases of the Liver and Gallbladder
1.9K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.9K
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
356
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
356
Assessment of the Gastrointestinal System II: Health Perception Pattern
456
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
456
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
373
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
373
Chi-square Analysis
43.6K
The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
43.6K
