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挑战和突破:CAR-T细胞治疗实体瘤临床试验的现状和未来前景

Jing Guo1, Chunhe Zhou1, Hongmei Zhao1

  • 1The Affiliated Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang, China.

Frontiers in oncology
|September 19, 2025
PubMed
概括

化学抗原受体T细胞 (CAR-T) 疗法对固体瘤具有前景,但抗原逃逸和瘤微环境等挑战仍然存在. 未来的战略重点是优化CAR-T设计和组合疗法,以获得更广泛的临床应用.

关键词:
在CAR-T细胞疗法中.抗原逃逸的方法是什么?临床试验是指临床试验中的临床试验.固体瘤是一种固体瘤.瘤微环境是一个微环境.

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