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Updated: Jan 17, 2026

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
04:36

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors

Published on: October 17, 2025

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IONPs与细胞氨基酸结合下调IFITM3表达,以抑制急性髓性白血病

Jun Dou1,2,3, Feng Mei2,4, Hui Xu2,5

  • 1Academic Affairs Office, Xinjiang Second Medical College, Karamay, Xinjiang Ugur Autonomous Region, China.

Frontiers in oncology
|September 19, 2025
PubMed
概括

铁氧化物纳米粒子 (IONPs) 与细胞氨基酸 (Ara-C) 结合,显示出治疗急性髓性白血病 (AML) 的前景. 这种组合疗法抑制IFITM3表达,减少癌细胞生长,并在AML模型中诱导细胞死亡.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.携带急性髓性白血病的小鼠细胞氨酸 (cytarabine) 是一种干扰素诱导的跨膜蛋白3 干扰素诱导的跨膜蛋白铁氧化物纳米粒子 铁氧化物纳米粒子有活性氧物种的反应性氧物种.

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