高海拔部落人口的认知功能:使用蒙特利尔认知评估 (MoCA) 工具进行评估
Hitesh Jani1, Punam Verma1, Ritika Thakur1
1Department of Physiology, All India Institute of Medical Sciences Bilaspur, Kothipura, Bilaspur, Himachal Pradesh, India.
Annals of neurosciences
|September 19, 2025
概括
高海拔对认知功能产生负面影响,海拔和年龄的增加与命名,注意力和记忆的分数较低有关. 在视觉空间/执行和注意力任务中,男性的得分通常高于女性.
科学领域:
- 生理学 生理学 生理学
- 神经科学是一个神经科学.
- 人类学是人类学.
背景情况:
- 处于高海拔地区 (HA) 的慢性缺氧会影响认知功能.
- 有限的研究存在于本地HA种群的认知功能.
研究的目的:
- 评估印度希马查尔邦 (Himachal Pradesh) 部落人口的认知功能.
- 用蒙特利尔认知评估 (MoCA) 来评估高海拔,年龄和性别对HA本地人的认知功能的影响.
主要方法:
- 使用MoCA工具评估了359名HA本地人的认知功能.
- 参与者按高度 (3,000-3,500米和>3,500米) 和年龄 (20-40,41-60,>60岁) 分层.
- 统计分析发现了高度,年龄,性别和MoCA分数之间的关联.
主要成果:
- 较高的海拔高度与命名,注意力,延迟回忆和定向等较低的分数相关 (p < .001).
- 年龄对大多数领域的MoCA得分有显著影响 (p < .001),随着年龄的增长呈现下降.
- 发现了性别差异,男性在视觉空间/执行和注意力分量表中表现优于女性 (p < .001).
结论:
- 越来越高的高度与特定认知领域的表现下降有关.
- 年龄是HA本地人的认知表现的一个重要因素,随着年龄的增长,得分会下降.
- 高度,年龄和性别是高海拔人口认知特征的关键决定因素.
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