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Updated: Jan 17, 2026

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分子对接,分子动力学模拟和ADME分析基于佐的新型OGT抑制剂

Tanisqa Mall1, Parteek Prasher1, Macarena Loncón-Pavez2

  • 1Department of Chemistry, Energy Acres, University of Petroleum & Energy Studies, Dehradun, 248007 India.

In silico pharmacology
|September 19, 2025
PubMed
概括

研究人员探索了佐沙-氨基酸合物作为O-GlcNAc转移酶 (OGT) 的潜在抑制剂. 酸性形式显示出更好的结合,而形式则充当前药物,平衡新药开发的疗效和生物可用性.

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