青春期和年轻成年期的大麻使用及其对大脑结构和功能的影响:一个范围审查
Lilith Nosko1,2, Candice E Crocker1,3, Phil G Tibbo1,2
1Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.
Frontiers in psychiatry
|September 19, 2025
概括
青春期和年轻成年期 (14-25岁) 的大麻使用与大脑变化有关. 虽然大多数研究表明大脑结构和功能存在差异,但需要更多高质量的研究.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 成研究 研究成研究
背景情况:
- 青春期和年轻成年期是大脑发育的关键时期.
- 这一生命阶段往往与大麻使用的开始相吻合.
- 了解早期大麻暴露对发育中的大脑的影响至关重要.
研究的目的:
- 进行神经成像研究的范围审查.
- 总结大麻使用 (14-25岁) 对大脑结构,功能和代谢物度的影响.
- 识别当前研究中的差距和局限性.
主要方法:
- 对神经成像研究的数据库进行系统搜索.
- 纳入标准集中在14-25岁之间的大麻使用.
- 分析检查大脑结构,功能和代谢物度的研究.
主要成果:
- 99项研究符合来自3901个来源的纳入标准.
- 大多数研究 (84/99) 报告了青少年/年轻成年大麻使用者大脑的差异.
- 较少的研究探讨了性别/性别差异,其中5项表明了影响.
结论:
- 相当多的证据表明,青春期/青春期大麻使用会改变大脑发育.
- 研究的低质量和异质性限制了最终的结论.
- 进一步的长期,高质量的研究是必要的,以充分理解早期大麻使用和大脑变化之间的关系.
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