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住院患者严重自发性低血糖症相关的风险因素和死亡率:一项回顾性队列研究
Daniel Pazos Pinto1,2, Alina Coutinho Rodrigues Feitosa1,2
1¹Department of Internal Medicine, Santa Izabel Hospital, Salvador, Bahia Brazil.
严重自发性低血糖 (SSH) 影响0.81%的住院患者,与66%的死亡率有关. 虽然复发很常见,但它不会显著增加死亡率,但SSH表明严重的疾病.
科学领域:
- 临床医学 临床医学
- 内分泌学 在内分泌学.
- 关键的护理关键的护理
背景情况:
- 严重自发性低血糖 (SSH) 是一种罕见但高风险的住院患者的病症,特别是在危急病患者中.
- SSH与死亡率增加有关,可以作为疾病严重程度的标志物.
研究的目的:
- 描述SSH患者的住院死亡率和临床特征.
- 分析与SSH相关的因素及其在医院环境中的结果.
主要方法:
- 在圣伊莎贝尔医院进行了一项回顾性队列研究.
- 分析了47名患有严重低血糖症 (≤40毫克/分升) 的患者,不包括胰岛素使用者和测量错误.
- 收集了有关人口统计,并发症,低血糖复发和医院结局的数据.
主要成果:
- SSH的患病率为0.81%,在医院内死亡率为66%.
- 在24小时内复发发生在46.8%的患者中,但与增加的死亡率没有显著关联.
- 与幸存者相比,死亡的患者患上了更多的并发症,肌素升高,乳酸盐水平更高.
结论:
- 虽然SSH很罕见,但与显著增加的住院死亡率有关.
- SSH通常发生在快速的临床恶化期间,许多人在最初的发作后24小时内死亡.
- SSH可以作为疾病严重程度的关键标志物和指导患者管理的预后指标.
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