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大麻素CB1受体激活减轻N-甲基-d-阿斯巴酸受体介导的神经毒性

Gemma Navarro1,2,3, Iu Raïch1,2,3, Joan Biel Rebassa1,2,3

  • 1Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health Carlos III, 28031 Madrid, Spain.

ACS pharmacology & translational science
|September 19, 2025
PubMed
概括

这项研究揭示了大麻素CB1受体和NMDA受体之间的直接相互作用,这对阿尔茨海默病的病理学至关重要. 调节这种相互作用可以提供神经保护,防止刺激毒性和Aβ诱导的损伤.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.这种NMDA受体是NMDA受体.激发性有毒性 激发性有毒性功能选择性的功能选择性.神经保护神经保护接收器-接收器相互作用一些信号,一些信号.

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