儿科中Actinobacillus ureae脑膜炎:一个罕见的临床病例
Najlae Ouamna1, Asmae Lamrani Hanchi1, Taoufik Ben Houmich1
1Microbiology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Marrakech, MAR.
Cureus
|September 19, 2025
概括
尿素细菌脑膜炎是罕见的,但可治疗的,特别是在头部创伤或神经外科病史的儿童中. 及时诊断和塞夫特里亚克森治疗在这种情况下导致了有利的结果.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
背景情况:
- 在头部创伤和神经外科手术后,儿童出现复发性脑膜炎.
- 呈现急性脑膜综合征与临床恶化.
研究的目的:
- 报告一例罕见的Actinobacillus ureae脑膜炎病例,发生在儿童患者身上.
- 为突出诊断挑战和治疗结果的尿素菌感染.
主要方法:
- 脑脊液分析包括显微镜,培养和多重PCR.
- 通过质谱测量 (VITEK® 2 MS) 来识别菌菌.
- 抗生素测试以确定对抗生素的敏感性.
主要成果:
- 培养分离了Actinobacillus ureae,而多重PCR则是负的.
- 该病原体对阿莫西西林,塞夫triaxone,trimethoprim-sulfamethoxazole和siprofloxacin敏感.
- 这位患者成功接受了10天的 ceftriaxone 疗程,显示了临床和生物上的改善.
结论:
- 在有头部创伤或神经外科手术史的患者中,应考虑Actinobacillus ureae脑膜炎.
- 早期诊断和适当的抗生素治疗,如 ceftriaxone,对于有利的结果至关重要.
- 当传统技术无法识别致病原体时,可能需要先进的诊断方法.
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