喉回流患者的语音结果:系统性审查和元分析
Jaisingh Rajput1, Cheikh S Mballo2, Mohamed Elahtem3
1Family Medicine, Montgomery Family Medicine Residency Program, Baptist Health, Montgomery, USA.
Cureus
|September 19, 2025
概括
行为疗法比治疗喉回流 (LPR) 语音问题的药物更有效. 诊断准确性和长期坚持对于管理LPR相关的语音问题至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 语音语言病理学 语音语言病理学
- 胃肠病学 胃肠病学
背景情况:
- 喉回流 (LPR) 经常导致声音障碍.
- 目前针对语音问题的LPR治疗方法的有效性受到争议.
- 需要对LPR患者语音结果的证据进行系统审查.
研究的目的:
- 综合LPR患者语音结果的证据.
- 为了评估与LPR相关的语音功能障碍的药理学,行为和诊断方法的有效性.
- 为了比较不同干预和诊断方法的有效性.
主要方法:
- 根据系统审查和元分析 (PRISMA) 标准的首选报告项目进行了系统审查.
- 分析了2000年至2024年间发表的八项研究的数据.
- 随机效应的元分析被用来评估效应大小,异质性和子组差异.
主要成果:
- 包括语音治疗和李·西尔弗曼语音治疗 (LSVT) 在内的行为干预措施显示出强大的疗效 (ES=0.60).
- 质子抑制剂 (PPI) 的效果是可以忽略不计的 (ES = -0.15),而辅助的Rikkunshito在耐火病例中改善了结果 (ES = 0.82).
- 像声学分析和语音障碍指数 (VHI) 这样的诊断方法比临床症状或反流症状指数 (RSI) (ES=0.32) 更可靠 (ES=0.56). 长期收益是不一致的 (ES=0.25).
结论:
- 行为疗法优于与LPR相关的语音功能障碍的药理疗法.
- 准确的诊断和持续的患者坚持是成功LPR管理的关键.
- 未来的研究应该集中在标准化诊断方案和多式联络治疗策略上.
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