在患有高血压的成年人中,腕脉冲波速度在第一次中风时的和效应:一个前性队列研究

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Updated: Jan 17, 2026

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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

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Wei Zhou^1,2, Lingjuan Zhu^1,2, Tao Wang^1,2

¹Center for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.

Frontiers in cardiovascular medicine

|September 19, 2025

概括

脚脉冲波速率 (baPWV) 显示了中国高血压成年人中风风险的和效应. 在17.5m/s以上,baPWV不会显著增加中风风险,这表明潜在的值.

科学领域:

心血管医学心血管医学
高血压研究高血压研究
预防中风预防中风

背景情况:

以前的研究表明,脚脉冲波速度 (baPWV) 与高血压患者中风之间存在线性联系,主要来自非中国人群.
在中国,关于这种关联的研究有限,这突显了区域理解的差距.

研究的目的:

研究baPWV对高血压的中国成年人首次中风风险的和效应.
确定baPWV的潜在转折点,即中风风险高原.

主要方法:

利用了中国高血压注册研究中的7,198名高血压成年人的数据.
采用考克斯比例危险回归,限制立方脊柱平滑和卡普兰-梅尔生存分析来评估baPWV对首次中风事件的影响.

主要成果:

观察到baPWV在第一冲击时具有和效应,其拐点为17.5 m/s.
对于baPWV<17.5m/s,每1m/s的增加与中风风险增加31%相关 (HR: 1.31).
对于baPWV≥17.5m/s,没有发现与中风风险的显著关联 (HR:0.99).

结论:

脚脉冲波速度 (baPWV) 证明了中国高血压成年人首次中风风险的和效应.
升高的baPWV (<17.5 m/s) 与中风风险增加有关,但这种关联在较高的baPWV值下降.

关键词:

腕脉冲波速波速波速波速年长的老人老年人老年人.这种高血压,高血压.和效应是一种和效应.一次性中风中风中风中风中风

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