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Updated: Jan 17, 2026

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

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PKD3局限于晚期内分泌体,以维持Rab7依赖的内分泌体平衡

Elena Gutiérrez-Galindo1, Katharina Jursik1, Yannick Frey2

  • 1Institute of Cell Biology and Immunology, University of Stuttgart, Allmandring 31, 70569 Stuttgart, Germany.

iScience
|September 19, 2025
PubMed
概括

蛋白激酶D3 (PKD3) 调节三阴性乳腺癌 (TNBC) 的进展. PKD3控制了内分泌体动态,通过影响囊泡大小和Wnt信号来影响癌症干细胞的维持.

关键词:
生物科学 生物科学发育生物学是发展生物学.分子生物学分子生物学

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The Microscopy-Based Assay to Study and Analyze the Recycling Endosomes using SNARE Trafficking08:51

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Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation12:49

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

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The Early Endosome: Endocytosis of Transferrin

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The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
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