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Updated: Jan 17, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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对BCG不响应的非肌肉侵入性膀癌的基因介导疗法:机制,临床证据和实际实施

Chris Ho-Ming Wong1, David Ka-Wai Leung1, Paolo Gontero2

  • 1S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Current opinion in urology
|September 19, 2025
PubMed
概括

基因疗法为高风险,Bacillus Calmette-Guérin (BCG) 不响应的非肌肉侵入性膀癌 (NMIBC) 提供了一种有前途的膀节约方法. 在分娩和组合疗法的进步正在改善膀的保存和患者的结果.

关键词:
巴西勒斯卡尔梅特-盖林无反应的非肌肉侵入性膀癌.腺病毒载体 (nadofaragene firadenovec) 的使用静脉内基因疗法 静脉内基因疗法非病毒性等离子体疗法 (detalimogene voraplasmid/EG-70) 是一种非病毒性等离子体治疗.型腺病毒 (cretostimogene/CG0070) 的使用.

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