通过与RPA集成,用于可视检测B组Streptococcus的无提取和单两温度CRISPR/Cas12b系统

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Updated: Jan 17, 2026

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
07:59

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

Published on: April 25, 2025

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Chengman Zhao1, Ge Li2, Chen Shen3

  • 1Department of Internal Medicine, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Journal of clinical microbiology
|September 19, 2025
PubMed
概括

这项研究开发了一种快速,无提取的CRISPR/Cas12b试验,用于检测B组链球菌 (GBS). 优化的方法实现了高灵敏度的GBS检测,适合于点的护理应用.

关键词:
这就是CRISPR/Cas12b.B组的链球菌.一个灯的灯光.在 RPA RPA 中使用.没有提取的自由提取.一个的两个温度.

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相关概念视频

CRISPR and crRNAs02:53

CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
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